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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARNTL All Species: 26.36
Human Site: S462 Identified Species: 52.73
UniProt: O00327 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00327 NP_001025443.1 626 68762 S462 Q L T A S P H S M D S M L P S
Chimpanzee Pan troglodytes XP_001171687 626 68743 S462 Q L T A S P H S M D S M L P S
Rhesus Macaque Macaca mulatta XP_001095200 626 68713 S462 Q L T A S P H S M D S M L P S
Dog Lupus familis XP_851850 634 69695 S469 Q L T A S P H S M D S M L P S
Cat Felis silvestris
Mouse Mus musculus Q9WTL8 632 69433 S468 Q L T A P P H S M D S M L P S
Rat Rattus norvegicus Q9EPW1 626 68597 S462 Q L T A S P H S M D S M L P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507514 398 44707 F248 S T N Q S M V F N T I K V F H
Chicken Gallus gallus Q9I8T7 633 69419 S469 Q L A A S P H S M D S V L Q A
Frog Xenopus laevis NP_001089024 627 68721 N467 H L S T S P P N M N S V L Q S
Zebra Danio Brachydanio rerio Q9DG12 737 80954 A474 H Q R D G L T A Y D L S Q V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61734 413 47551 K263 L K S W T P I K D E D Q D A D
Honey Bee Apis mellifera XP_001121441 739 82052 G561 S E D S S V Q G N Y D Y F A Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 99.8 97.6 N.A. 97.3 98.2 N.A. 52.8 93.2 85.8 31.6 N.A. 35.2 42.6 N.A. N.A.
Protein Similarity: 100 100 99.8 98.4 N.A. 97.7 98.8 N.A. 55.4 95 91 49.9 N.A. 48.5 55.6 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 6.6 73.3 46.6 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 13.3 86.6 73.3 13.3 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 59 0 0 0 9 0 0 0 0 0 17 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 0 0 0 0 9 67 17 0 9 0 9 % D
% Glu: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 0 9 9 0 % F
% Gly: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % G
% His: 17 0 0 0 0 0 59 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 0 9 0 0 0 9 0 0 0 % K
% Leu: 9 67 0 0 0 9 0 0 0 0 9 0 67 0 0 % L
% Met: 0 0 0 0 0 9 0 0 67 0 0 50 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 9 17 9 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 75 9 0 0 0 0 0 0 50 9 % P
% Gln: 59 9 0 9 0 0 9 0 0 0 0 9 9 17 9 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 0 17 9 75 0 0 59 0 0 67 9 0 0 59 % S
% Thr: 0 9 50 9 9 0 9 0 0 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 9 9 0 0 0 0 17 9 9 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 9 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _